C Auris

Q: The drug of choice for Candida Auris is fluconazole.

A) True

B) False

Answer: B

C. Auris has become a subject of high concern due to its resistance and recent high transmission in health care facilities across the United States. Centers for Disease Control and Prevention (CDC) is still accumulating data and trying to figure out the sudden rise of this candida.

C. Auris has been found highly resistant to fluconazole. MIC resistance breakpoints 

• ≥32 mcg/mL for fluconazole
• ≥2 mcg/mL for amphotericin B
• ≥2 mcg/mL for caspofungin
• ≥4 mcg/mL for anidulafungin and micafungin

#ID

References:

1. Tsay S, Kallen A, Jackson BR, et al. Approach to the Investigation and Management of Patients With Candida auris, an Emerging Multidrug-Resistant Yeast. Clin Infect Dis 2018; 66:306.

2. Centers for Disease Control and Prevention. Candida auris. Antifungal Susceptibility Testing and Interpretation. https://www.cdc.gov/fungal/candida-auris/c-auris-antifungal.html (Accessed on September 25, 2022).