Wednesday, November 2, 2022

3 "Pseudos" of Thrombocytosis

Q: Name (at least) 3 "Pseudos" of Thrombocytosis (high platelet counts)?

Answer: Browsing platelet count is a good habit before interpreting other labs. High platelet count, i.e., thrombocytosis may cause
  • Pseudo-hyperkalemia 
  • Pseudo-hyperphosphatemia 
  • Pseudo-hyper-acid phosphatase 
  • Pseudo-hypoxemia (even on ABG) 

#hematology
#lab-medicine



References: 

1. Pseudo-hyperkalemia and thrombocytosis - Ann Biol Clin (Paris). 2003 Nov-Dec;61(6):696-8

2. The effect of thrombocytosis on serum potassium and phosphorus concentrations - The American journal of the medical sciences 1994, vol. 307, n 4, pp. 255-258 (19 ref.) - http://cat.inist.fr/?aModele=afficheN&cpsidt=4062835

3. Platelet-derived acid phosphatase isoenzyme in the serum in thrombocythemia - Am J Clin Pathol.1977 Feb;67(2):177-9

4. Platelet larceny: spurious hypoxaemia due to extreme thrombocytosis - Eur Respir J 2008; 31:469-472

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