Q: How stool softener docusate works?
Answer: Stool softeners are frequently used in ICU for constipation. Very few people know that actually, its mechanism of action is due to its property of surfactant. It lowers the surface tension of stool. This allows water to easily enter the stool. This is for the same reason they are effective as ear wax removers!!
#pharmacology
References:
1. Bharucha AE, Pemberton JH, Locke GR 3rd. American Gastroenterological Association technical review on constipation. Gastroenterology 2013; 144:218.
2. Singer AJ, Sauris E, Viccellio AW. Ceruminolytic effects of docusate sodium: a randomized, controlled trial. Ann Emerg Med. 2000 Sep;36(3):228-32. doi: 10.1067/mem.2000.109166. PMID: 10969225.
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