Q: 62 years old male who consumes many over the counter (OTC) nutritional products including vitamins and omega-3 fatty acid is admitted to ICU with atrial fibrillation (AF). Omega-3 fatty acid may have contributed to his AF?
A) True
B) False
Answer: A
There is a weak evidence from few cardiovascular studies that omega-3 fatty acids may be associated with an increased risk of AF. A meta-analysis composed of more than 80,000 patients and seven randomized controlled trials (RCTs) showed Hazard Ratio (HR) of 1.25 of AF association with omega-3 fatty acids.
#cardiology
Reference:
Gencer B, Djousse L, Al-Ramady OT, et al. Effect of Long-Term Marine ɷ-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis. Circulation 2021; 144:1981.
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