Behçet syndrome

Q: Behçet syndrome involves the vessels of? (select one)

A) large size

B) medium size

C) small size

D) all sizes 

Answer: D

Behçet syndrome is a form of vasculitis and can involve blood vessels of all sizes as well as both the arterial and venous sides of the circulation. In contrast to many vasculitides, it is more common in men

Its major clinical manifestations are

• Deep venous thrombosis DVT)
• Subcutaneous thrombophlebitis
• Venal Caval occlusions
• Cerebral sinus thrombosis
• Budd-Chiari syndrome
• Pulmonary artery occlusion or aneurysm
• Aortic aneurysm
• Extremity arterial occlusion or aneurysm

#rheumatology

References:

1. Koc, Y, Gullu, I, Akpek, G, et al. J Rheumatol 1992; 19:402.

2. Hamuryudan V, Er T, Seyahi E, et al. Pulmonary artery aneurysms in Behçet syndrome. Am J Med 2004; 117:867.

3. Zouboulis CC, Vaiopoulos G, Marcomichelakis N, et al. Onset signs, clinical course, prognosis, treatment and outcome of adult patients with Adamantiades-Behçet's disease in Greece. Clin Exp Rheumatol 2003; 21:S19.

4. Zou J, Luo JF, Shen Y, et al. Cluster analysis of phenotypes of patients with Behçet's syndrome: a large cohort study from a referral center in China. Arthritis Res Ther 2021; 23:45.

5. Yazici H, Ugurlu S, Seyahi E. Behçet syndrome: is it one condition? Clin Rev Allergy Immunol 2012; 43:275.

6. Yazici Y, Hatemi G, Bodaghi B, et al. Behçet syndrome. Nat Rev Dis Primers 2021; 7:67.