leucoreduction

Q: Leukoreduction in transfused blood products is performed? (select one)

A) at the time of blood collection

B) at the end of storage/delivery

Answer: A

Leukoreduction is in simple words filtering out white blood cells using an in-line filter. It is done at the time of blood collection. It is also called "pre-storage leukoreduction." The step helps in decreasing febrile nonhemolytic transfusion reactions (FNHTRs). Moreover, it also decreases the risk of cytomegalovirus (CMV) infection. 

#blood-bank

#hematology

References:

1. Bianchi M, Vaglio S, Pupella S, Marano G, Facco G, Liumbruno GM, Grazzini G. Leucoreduction of blood components: an effective way to increase blood safety? Blood Transfus. 2016 May;14(2):214-27. doi: 10.2450/2015.0154-15. Epub 2015 Dec 16. PMID: 26710353; PMCID: PMC4918553.

2. Bilgin YM, van de Watering LM, Brand A. Clinical effects of leucoreduction of blood transfusions. Neth J Med. 2011 Oct;69(10):441-50. PMID: 22058263.