"pseudos" of thrombocytosis

Q: Name at least three "pseudo" abnormalities in the lab that may occur due to thrombocytosis? 

Answer: Thrombocytosis in serum can cause other lab abnormalities, and may deceive clinicians as these are mostly pseudo conditions. The most well-known are

• Pseudo-hyperkalemia
• Pseudo-hyperphosphatemia
• Pseudo-hyper-acid phosphatase
• Pseudo-hypoxemia (even on ABG)

#lab-medicine

#electrolytes

#hematology

References:

1. Pseudo-hyperkalemia and thrombocytosis - Ann Biol Clin (Paris). 2003 Nov-Dec;61(6):696-8

2. The effect of thrombocytosis on serum potassium and phosphorus concentrations - The American journal of the medical sciences 1994, vol. 307, n 4, pp. 255-258 (19 ref.) - If pop-up is block, cut and paste in browser, http://cat.inist.fr/?aModele=afficheN&cpsidt=4062835

3. Platelet-derived acid phosphatase isoenzyme in the serum in thrombocythemia - Am J Clin Pathol.1977 Feb;67(2):177-9

4. Platelet larceny: spurious hypoxaemia due to extreme thrombocytosis - Eur Respir J 2008; 31:469-472