Saturday, January 20, 2024

WE and gender paradox

Q: Females are more prone to develop Wernicke encephalopathy (WE)?

A) True
B) False


Answer: A

It is interesting that though epidemiologically the ratio of men to women for WE is way higher, but if the ratio for alcohol dependence is taken into consideration the female-to-male ratio for WE is higher.

Although various reasons have been proposed for this paradox such as the female gender is more prone to anorexia nervosa, hyperemesis of pregnancy, or malnutrition worldwide - still it is not fully explained.


#neurology


References:

1. Victor M, Adams RA, Collins GH. The Wernicke-Korsakoff syndrome and related disorders due to alcoholism and malnutrition, FA Davis, Philadelphia 1989.

2. Harper C. The incidence of Wernicke's encephalopathy in Australia--a neuropathological study of 131 cases. J Neurol Neurosurg Psychiatry 1983; 46:593.

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