Q: Which patients usually get labeled as Rhupus?
Answer: Patients often have combined or overlapping features of Systemic Lupus Erythematosus (SLE) and Rheumatic Arthritis (RA). There are no objective criteria, either clinically and/or immunologically, to describe it as a distinct disease.
One of the clinical features that characterized these patients is erosive arthropathy, which is unlikely to present in SLE.
#rheumatology
References:
1. Antonini L, Le Mauff B, Marcelli C, Aouba A, de Boysson H. Rhupus: a systematic literature review. Autoimmun Rev. 2020 Sep;19(9):102612. doi: 10.1016/j.autrev.2020.102612. Epub 2020 Jul 12. PMID: 32668290.
2. Upadhyaya S, Agarwal M, Upadhyaya A, Pathan.ia M, Dhar M. Rhupus Syndrome: A Diagnostic Dilemma. Cureus. 2022 Sep 11;14(9):e29018. doi: 10.7759/cureus.29018. PMID: 36249648; PMCID: PMC9550206.
3. Ahsan H. Rhupus: dual rheumatic disease. J Immunoassay Immunochem. 2022 Mar 4;43(2):119-128. doi: 10.1080/15321819.2021.1941096. Epub 2021 Jul 6. PMID: 34228594
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