Q; 17 years old male, a foster home resident, is admitted to ICU with severe diarrhea and hypotension. While evaluating patient, GI service ordered NIRA. What is the advantage of Near infrared reflectance Analysis (NIRA) over other tests for severe malabsorption?
Answer: Though NIRA is less frequently used in USA than in other parts of the world, it almost accurately and quickly measures all the three dietary components, i.e., fecal fat, nitrogen, and carbohydrates, from a single sample. It does not require 72-hour fecal fat collection. It is an excellent tool for diagnosing malabsorption.
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References:
1. Neumeister V, Henker J, Kaltenborn G, et al. Simultaneous determination of fecal fat, nitrogen, and water by near-infrared reflectance spectroscopy. J Pediatr Gastroenterol Nutr 1997; 25:388.
2. Stein J, Purschian B, Zeuzem S, et al. Quantification of fecal carbohydrates by near-infrared reflectance analysis. Clin Chem 1996; 42:309.
3.Bekers O, Postma C, Fischer JC, et al. Faecal nitrogen determination by near-infrared spectroscopy. Eur J Clin Chem Clin Biochem 1996; 34:561.
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