Q: 26 weeks pregnant lady is admitted to ICU with hypertensive crisis. This is her third admission in the last few weeks and had required multiple endeavors to control her blood pressure. The rotating resident suggested Nitroprusside. Suggestion should be entertained, and Nitroprusside is a good idea.
A) True
B) False
Answer: B
Nitroprusside is either absolutely or relatively contraindicated in at least five conditions
- pregnancy
- Leber optic atrophy
- tobacco amblyopia
- renal insufficiency
- sulfa allergy
#pharmacology
#ob-gyn
References:
1. Hottinger DG, Beebe DS, Kozhimannil T, Prielipp RC, Belani KG. Sodium nitroprusside in 2014: A clinical concepts review. J Anaesthesiol Clin Pharmacol. 2014 Oct;30(4):462-71. doi: 10.4103/0970-9185.142799. PMID: 25425768; PMCID: PMC4234779.
2. Holme MR, Sharman T. Sodium Nitroprusside. 2023 May 22. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32491419.
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