Q: What care should be taken on giving Linezolid (Zyvox) to patients who are on HD (hemodialysis)?
Answer: Administer after HD session as about 40% of drug is removed via HD. This point is usually get missed as in normal circumstances, Linezolid does not require any adjustment in renal insufficiency.
Linezolid get metabolized via liver but does require any adjustment in mild to moderate liver insufficiency, either.
Patients on CRRT does not require any adjustments but may require higher/more frequent administration.
Answer: Administer after HD session as about 40% of drug is removed via HD. This point is usually get missed as in normal circumstances, Linezolid does not require any adjustment in renal insufficiency.
Linezolid get metabolized via liver but does require any adjustment in mild to moderate liver insufficiency, either.
Patients on CRRT does not require any adjustments but may require higher/more frequent administration.
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