Q: Why Glycopyrrolate is always used with Neostigmine for 'reversal' of neuromuscular blockade after surgery?


Answer:  Glycopyrrolate is used in conjunction with neostigmine, a neuromuscular blocking reversal agent, to prevent neostigmine's muscarinic effects particularly bradycardia. In case if not available (as recently, the shortage status in USA), atropine can be used.