Wednesday, January 15, 2014

Q: Is Amiodarone dialyzable?


Answer: No

Amiodarone's excretion is primarily hepatic and biliary with almost no elimination via the renal route. Also, it is not dialyzable. It has elimination half-life average of 58 days, and 36 days for its active metabolite, desethylamiodarone (DEA). Accumulation of amiodarone and DEA occurs in adipose tissue and highly perfused organs i.e. liver, lungs. 


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