icupearls.org Archive
Pearls on Intensive Care Medicine Practice - Project "Critical Care A Day"
Friday, January 31, 2014
Q:
What is the rule of thumb of dosing Argatroban in patients with significant liver dysfunction?
Answer:
Decrease dose by 75%
The dose should be adjusted by aPTT with a target of 1.5-3 times the baseline.
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