Q: How Transfusion-Associated Circulatory Overload (TACO) can be clinically distinguished from Transfusion-Related Acute Lung Injury (TRALI)?

Answer: TACO typically responds to diuretics with symptomatic improvement, while TRALI is usually unresponsive to diuretics. Moreover, TRALI usually presents with hypotension and TACO with hypertension, given other cardiovascular and renal conditions stable.