Q: Which of the following has the most sedative effect? (select one)
A) Hydroxyzine
B) Benzodiazepines
C) Buspirone
Answer: A
Hydroxyzine has more sedative properties than benzodiazepines and buspirone. Due to this effect, hydroxyzine is widely use in Generalized Anxiety Disorder (GAD). The good sleep effect eventualy helps reduce the overall anxiety.
#psychiatry
#pharmacology
Reference:
1. Burgazli CR, Rana KB, Brown JN, Tillman F 3rd. Efficacy and safety of hydroxyzine for sleep in adults: Systematic review. Hum Psychopharmacol. 2023 Mar;38(2):e2864. doi: 10.1002/hup.2864. Epub 2023 Feb 26. PMID: 36843057.
2. Guaiana G, Barbui C, Cipriani A. Hydroxyzine for generalised anxiety disorder. Cochrane Database Syst Rev 2010; :CD006815.
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