Wednesday, February 29, 2012

Q; Which supplement intake may help in preventing Coronary artery vasospasm (Prinzmetal Angina)?

Answer: Magnesium

Magnesium deficiency heighten sensitivity to acetylcholine- and hyperventilation-induced coronary artery spasm. Magnesium supplementation may help as a useful therapy.

Monday, February 27, 2012

Q; Each 15 mL unit of Cryoprecipitate typically contains how much of fibrinogen? 

Answer: Each 15 mL unit of Cryoprecipitate typically contains 250 mg of fibrinogen
It also contains 100 IU of factor VIIIvon Willebrand factor (vWF) and factor XIII.
FDA standards requires that the product must have an average of 150 mg or more of fibrinogen and 80 IU of factor VIII.

Sunday, February 26, 2012


Clinical experience with power injectable peripherally inserted central catheters in intensive care patients 


In intensive care units (ICU), peripherally inserted central catheters (PICC) may be an alternative option to standard central venous catheters, particularly in patients with coagulation disorders or at high risk for infection. Some limits of PICCs (such as low flow rates) may be overcome by the use of power-injectable catheters.


We have retrospectively reviewed all the power injectable PICCs inserted in adult and pediatric patients in the ICU during a 12-month period, focusing on the rate of complications at insertion and during maintenance.


We have collected 89 power injectable PICCs (in adults and in children), both multiple and single lumen. All insertions were successful. There were no major complications at insertion and no episodes of catheter-related blood stream infection. Non-infective complications during management were not clinically significant. There was one episode of symptomatic thrombosis during the stay in ICU and one episode after transfer of the patient in a non-intensive ward.

Power injectable PICCs have many advantages in the ICU: they can be used as multi-purpose central lines for any type of infusion including high flow infusion, for hemodynamic monitoring, and for high-pressure injection of contrast media during radiological procedures. Their insertion is successful in 100% of cases and is not associated with significant risks, even in patients with coagulation disorders. Their maintenance is associated with an extremely low rate of infective and non-infective complications.

Clinical experience with power injectable peripherally inserted central catheters in intensive care patients - Critical Care 2012, 16:R21, Published: 4 February 2012