Q: How the lab diagnosis can be made for Miller Fisher syndrome (MFS)?
Answer: Anti-GQ1b antibodies
Answer: Anti-GQ1b antibodies
Miller Fisher syndrome (MFS) is a variant of GBS (Guillain–Barré syndrome) accounting for approximately 5% of cases. Clinically it is diagnosed by a descending paralysis, proceeding in the reverse order of the more common form of GBS. It affects the eye muscles first and presents with the triad of
- ophthalmoplegia,
- ataxia, and
- areflexia
Also, Ataxia predominantly affects the gait and trunk, with the limbs relatively spared.
Anti-GQ1b antibodies are present in 90% of cases.
