Saturday, June 23, 2012

Q: What is the dose of Methylene blue in treatment of Methemoglobinemia? 

Answer: Methylene blue 1% solution (10 mg/ml) 1 to 2 mg/kg given intravenously slowly over five minutes followed by IV flush with normal saline. 

 In any case supplemental Oxygen should be administrated. 

 Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state.

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