Tuesday, April 23, 2013

On IV acetaminophen

 "Compared to oral acetaminophen, IV acetaminophen achieves a rapid elevation in plasma concentration and higher peak levels. The IV form achieves plasma levels rarely achieved by similar oral doses of acetaminophen and produces 75% higher central nervous system (CNS) bioavailability compared to the oral form. The analgesic effect peaks within one hour and lasts for four to six hours." 

 Read full article here 

Darrell Harrington, MD 
Chief, Division of General Internal Medicine 
Harbor-UCLA Medical Center, Los Angeles 

 Source: Today's Hospitalist

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