Wednesday, June 26, 2013

Q: 42 year male who developed acute Transverse Myelitis - failed treatment options with high dose steroids and plasma exchange . What could be your third salvage option?
Answer: Intravenous cyclophosphamide

If there is continued progression despite high dose IV steroid  and Plasma Exchange therapy, pulse dose of intravenous cyclophosphamide (800–1000 mg/m2) can be given with consultation of neurology and oncology services.

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