Sunday, January 12, 2014

Q: DKA (Diabetic Ketoacidosis) may present or along with upper GI bleed. What is the usual cause of it?

Answer: Erosion of esophagus

Upper gastrointestinal hemorrhage complicates 9% of diabetic ketoacidosis hospitalizations. The most common lesion is erosive esophagitis. Hemorrhage correlates with glucose level, admission to the ICU, duration of diabetes and the presence of diabetic complications.

Faigel DO, Metz DC .- Prevalence, etiology, and prognostic significance of upper gastrointestinal hemorrhage in diabetic ketoacidosis. - Dig Dis Sci. 1996 Jan;41(1):1-8.

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