Q: In which condition Pantoprazole (protonix) dose is IV 80 mg  q 12 hours?

Answer: Zollinger-Ellison Syndrome

The dosage of IV Pantoprazole in patients with hypersecretory conditions associated with Zollinger-Ellison Syndrome or other neoplastic conditions is about 80 mg q12 hours. The frequency of dosing can be adjusted to individual patient needs based on acid output measurements. In some patients, 80 mg q8 hours may be needed to maintain acid output below 10 mEq/h.