Q: 37 year old female is in ICU for suspected DVT. There is concern for HIT (Heparin induced Thrombocytopenia). Patient is clinically stable. Patient is therapeutic  Decision is made to stop Heparin and start Argatroban. How long should you wait before initiating Argatroban?

Answer:  About 3 hours

For Enoxaparin it is recommended to wait about 8 hours. All relevant labs should be checked before starting Argatroban.