Treatment of ITP in Emergency

Urgent increase in platelet count may be required in those patients requiring surgery, at high risk of bleeding, or with active central nervous system, gastrointestinal, or genitourinary bleeding that cannot be controlled.

Consensus guidelines suggest combination therapy with intravenous corticosteroids and IVIg. In patients with extremely low platelets and bleeding, platelet transfusions can produce a transient rise in platelets to help with hemostasis. 

Antiplatelet therapies and other medications affecting platelet counts should be discontinued.

Antifibrinolytic agents such as tranexamic acid and aminocaproic acid may be useful in preventing recurrent bleeding and may be of value in those patients requiring dental or surgical procedures