Coronary Perfusion Pressure is a very under appreciated concept in ICUs. Coronary perfusion pressure (CPP) refers to the pressure gradient that drives coronary blood pressure. It is the difference between the aortic diastolic pressure and left ventricular end-diastolic pressure.
During cardiac arrest, CPP is one of the most important variables associated with the likelihood of return of spontaneous circulation (ROSC). A CPP of at least 15 mmHg is considered to be necessary for ROSC.
CPP = ADP - LVEDP
It signifies the proper filling pressure and importance of arterial diastolic pressure.