Tumor Lysis syndrome causes hypocalcemia instead of hypercalcemia
Cairo and Bishop defined a classification system for tumor lysis syndrome dividing it into categories
Laboratory tumor lysis syndrome:
(abnormality in 2 or more of the following, occurring within three days before or seven days after chemotherapy).
- uric acid > 8 mg/dL or 25% increase
- potassium > 6 meq/L or 25% increase
- phosphate > 4.5 mg/dL or 25% increase
- calcium < 7 mg/dL or 25% decrease
Clinical tumor lysis syndrome:
(laboratory tumor lysis syndrome plus one or more of the following)
- increased serum creatinine (1.5 times upper limit of normal)
- cardiac arrhythmia or sudden death
Cairo MS, Bishop M (October 2004). "Tumour lysis syndrome: new therapeutic strategies and classification". Br. J. Haematol. 127 (1): 3–11.