Q: During Tumor Lysis Syndrome, often diuretic is required along with IV hydration to keep urine out-put @ 80-100 cc/hr. What added advantage Furosemide provides beside diuresis in Tumor Lysis Syndome (TLS)?

Answer:  In TLS if diuretic is required; loop diuretics such as furosemide is preferred because they not only induce diuresis, but may also treat hyperkalemia, which is one of the life-threatening manifestation of TLS.