Monday, November 23, 2015

Q: Correction of which of the following electrolyte abnormality has direct association with improvement of hepatic encephalopathy?

A) Hyponatremia
B) Hypokalemia
C) Hypocalcemia
D) Hypomagnesemia
E) Hypophosphatemia 

Answer:  B

Almost 50 years ago it was determined that hypokalemia increases the renal ammonia production and so correction of hypokalemia has direct and significant effect on treatment of hepatic encephalopathy.


Gabduzda GJ, Hall PW 3rd. Relation of potassium depletion to renal ammonium metabolism and hepatic coma. Medicine (Baltimore) 1966; 45:481.

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