Friday, January 15, 2016

Q: Putting following five together, which diagnosis comes to mind? 

  • Hypercalcemia
  • Elevated 1, 25-dihydroxyvitamin D level
  • 3rd degree AV block, particularly in a Japanese person 
  • Hyperprolactinemia
  • Elevated alkaline phosphatase level, when liver is involved

Answer: Sarcoidosis

Though ACE levels is widely described as a marker for Sarcoidosis, neither it is very sensitive nor specific, and so has poor prognostic value.Sarcoidosis is a generalized disease process and has been described depending on the organ involvement. Above five are other few classics found to be associated with Sarcoidosis.

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