Saturday, February 20, 2016

Q: Inhaled Nitric Oxide(NO) increases the risk of injury to which of the following organs

A) Liver

B) Bone marrow
C) Kidney
D) Brain
E) Adrenals

Answer:  C

A meta-analysis published by Afshari A. and Coll. showed that inhaled NO increases the risk of renal injury. It should continue to be used only as a short-term rescue therapy in right heart failure, pulmonary hypertension or in refractory hypoxemia. Also, methemoglobin levels should be monitored closely in those patients.


Afshari A, Brok J, Møller AM, Wetterslev J. Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) and acute lung injury in children and adults. Cochrane Database Syst Rev 2010; :CD002787

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