Sunday, March 13, 2016

Q: All of the following are the hallmark of Thrombotic thrombocytopenic purpura (TTP) except?

A) Increased lactate dehydrogenase (LDH)
B) Microangiopathic hemolytic anemia (MAHA) 
C) Increased haptoglobin level
D) Massively increased INR 
E)  Elevated bilirubin

Answer:  D

Interestingly and to make differential diagnosis easy, coagulation profile is almost always normal in TTP, unless until some other underlying disease like sepsis may cause DIC (Disseminated Intravascular Coagulation).

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