Q: Which infectious cause is prone to give acquired protein C deficiency?


Answer:  Meningococcemia causing purpura fulminans 

Other (mostly non-infectious) causes of acquired protein C deficiency are

• Acute thrombosis
• Warfarin therapy 
• Liver disease 
• Vitamin K deficiency 
• DIC

Reference:

Lorenzo Alberio, Bernhard Lämmle, and Charles T. Esmon - Protein C Replacement in Severe Meningococcemia: Rationale and Clinical Experience - Clin Infect Dis. (2001) 32 (9): 1338-1346.