Q: Should angiotensin-converting enzyme inhibitor (ACE-I) or angiotensin receptor blockers (ARBs) be hold to prevent Contrast Induced Nephropathy (CIN)? (Select one)
C) Not Clear
There is no convincing evidence present in literature to support the idea of withholding ACE inhibitors and/or ARBs to prevent CIN. Most of the time, it is done reflexly. Actually, they have been suggested as rather helpful, by blocking renin-angio II vasoconstriction.
It should be done only on case to case basis - and should not be held in mild renal insufficiency.
1. Rim MY, Ro H, Kang WC, et al. The effect of renin-angiotensin-aldosterone system blockade on contrast-induced acute kidney injury: a propensity-matched study. Am J Kidney Dis 2012; 60:576.
2. Rosenstock JL, Bruno R, Kim JK, et al. The effect of withdrawal of ACE inhibitors or angiotensin receptor blockers prior to coronary angiography on the incidence of contrast-induced nephropathy. Int Urol Nephrol 2008; 40:749.