Q: If hyperbaric oxygen is used as an adjuvant to treat deep tissue infection, what is the target tissue oxygen tension?


Answer: Above 300 mmHg

Hyperbaric Oxygen, popularly known as HBO is now increasingly used in tertiary care centers as an adjuvant treatment in deep tissue infections such as gas gangrene, necrotizing fasciitis, and Fournier's gangrene. It requires 2-3 sessions daily of HBO with target to keep tissue oxygen tension above 300 mmHg to inhibit clostridial spore and exotoxin production.


Reference:

Roth RN, Weiss LD. Hyperbaric oxygen and wound healing. Clin Dermatol 1994; 12:141.