Monday, July 10, 2017

Q: Why hemodialysis (HD) is more effective than fomepizole in methanol toxicity?

Answer: Early HD may be more effective in methanol toxicity since endogenous clearance of methanol in those treated with fomepizole is slow.


1.  Gonda A, Gault H, Churchill D, Hollomby D. Hemodialysis for methanol intoxication. Am J Med 1978; 64:749. 

2. Brent J, McMartin K, Phillips S, et al. Fomepizole for the treatment of methanol poisoning. N Engl J Med 2001; 344:424.

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