Q: What is the cut off point of D-Dimer to rule out Aortic dissection (AD)?
Answer: Below 500 ng/mL
D-dimer is a strong serum marker for acute dissection. Level below 500 ng/mL has a negative predictive value of 96 percent to rule out aortic dissection. But still it is not a standard in clinical practice, as AD has been reported in patients below 400 ng/mL.
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