Tuesday, November 14, 2017

Q: All of the following can be probable first signs of Malignant Hyperthermia (MH) except 

A) Hyperthermia 
B) Hypercarbia 
C) Sinus tachycardia 
D) Masseter muscle rigidity 
E) Generalized muscle rigidity

Answer: A

There is a huge misconception that hyperthermia is the first sign of MH. Actually not!

Atleast one study showed that hyperthermia was the first sign in MH in only about 8 percent of the cases, and the sole initial sign in about four  percent of cases. 

All other choices in question can be the initial presenting signs in MH.


Larach MG, Gronert GA, Allen GC, et al. Clinical presentation, treatment, and complications of malignant hyperthermia in North America from 1987 to 2006. Anesth Analg 2010; 110:498.

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