Angioedema

Q: Besides face, lips, larynx, uvula, extremities, and genitalia, which of the following organs are more prone to get affected by Angiotensin-converting-enzyme -Inhibitor (ACE-I) Induced Angio-edema?

A) Bowels
B) Kidney
C) Liver
D) Brain
E) Prostate



Answer: A

Intestinal angioedema due to ACE-I usually goes unnoticed as they are not apparently visible and mostly presents with colicky and tender abdominal pain. It mostly affects the small intestine. It is important to recognize as these patients can be at higher risk for life-threatening laryngeal angioedema. CT scan is usually diagnostic.

#pharmacology
#gastroenterology



References:

1. Chase MP, Fiarman GS, Scholz FJ, MacDermott RP. Angioedema of the small bowel due to an angiotensin-converting enzyme inhibitor. J Clin Gastroenterol. 2000;31(3):254-257. 

2 Schmidt TD, McGarth KM. Angiotensin-converting enzyme inhibitor angioedema of the intestine: a case report and review of the literature. Am J Med Sci. 2002;324(2):106-108.