Tuesday, April 24, 2018

10:70:70 rule of cryoprecipitate

Q; What is the 10:70:70 rule of cryoprecipitate? 

 Answer: Ten units of cryoprecipitate will raise the fibrinogen level approximately 70 mg/dL in a 70 kg recipient. 


Reference: 

 Levy JH, Welsby I, Goodnough LT. Fibrinogen as a therapeutic target for bleeding: a review of critical levels and replacement therapy. Transfusion 2014; 54:1389.

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