Thursday, April 26, 2018

Silicone embolism syndrome

Q: Silicone embolism syndrome is a clinical diagnosis?

A) True
B) False

Answer: A (True)

Silicone embolism syndrome which may occur after silicone injection for cosmetic and/or therapeutic therapy. It is very much like fat embolism syndrome and has the clinical triad of
  • hypoxemia, 
  • fever, and 
  • a petechial rash

The most devastating manifestation can be diffuse alveolar damage.

Treatment is supportive.


1. Chung KY, Kim SH, Kwon IH, et al. Clinicopathologic review of pulmonary silicone embolism with special emphasis on the resultant histologic diversity in the lung--a review of five cases. Yonsei Med J 2002; 43:152. 

2. Schmid A, Tzur A, Leshko L, Krieger BP. Silicone embolism syndrome: a case report, review of the literature, and comparison with fat embolism syndrome. Chest 2005; 127:2276.

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