"Levine sign" in cardiology

Q: What is  "Levine sign" in cardiology?

Answer: When a patient describes his or her chest pain during cardiac ischemia with a clenched fist in the center of the chest, it is known as "Levine sign". Patient classically used right arm to make a fist as the referred pain associated with ischemia mostly radiates to the left arm. Similarly, it has an Argentinian version (as described by an Argentinian cardiologist) named as "Cossio's Sign" where a patient uses his entire palm over the chest.

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Reference:

1. Edmondstone WM (1995). "Cardiac chest pain: does body language help the diagnosis?". BMJ. 311 (7021): 1660–1.