Q: Which "stool marker" can differentiate between inflammatory bowel disease (IBD) and any functional bowel disease?
Calprotectin and lactoferrin are two stool markers for inflammatory bowel disease. Out of these two, calprotectin is the most used. If fecal calprotectin is normal, a diagnosis of inflammatory disease is practically ruled out. Also, if it is elevated, it has a sensitivity of about 93 percent and specificity of 96 percent to have IBD. Calprotectin is also used to monitor disease activity and flare-ups.
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