Sunday, January 6, 2019

Anti-rejection meds pericarditis

Q: Cyclosporine associated pericarditis is more common after which organ transplant? (select one) 

 A) Heart 
 B) Kidney

 Answer: A

Post transplant pericarditis is common and can occur due to variety of reasons. Renal transplant patients are more at risk due to development of uremia. Other leading causes are cytomegalovirus and anti-rejection medications. 

Among anti-rejection medications, Sirolimus tends to do pericarditis more in renal transplant patients, while cyclosporine associated pericarditis is more common in post heart transplant patients.




1. Hastillo A, Thompson JA, Lower RR, et al. Cyclosporine-induced pericardial effusion after cardiac transplantation. Am J Cardiol 1987; 59:1220.

2. Sever MS, Steinmuller DR, Hayes JM, et al. Pericarditis following renal transplantation. Transplantation 1991; 51:1229.

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