Monday, April 29, 2019

thiamine def

Q: Hemodialysis or peritoneal dialysis causes the loss of? (select one)

A) Water soluble vitamins
B) Fat soluble vitamins

Answer: A

Although it may be easy to guess the answer as dialysis serves the purpose of euvolemia, the objective of the above question is to pinpoint the loss of a very important vitamin, Thiamine. There is a misconception that thiamine is only deficient in chronic alcoholism patients. Thiamine is water-soluble and can be deficient in many other situations like anorexia nervosa, hyperemesis of pregnancy, total parental nutrition (TPN) and starvation.




Hung SC, Hung SH, Tarng DC, et al. Thiamine deficiency and unexplained encephalopathy in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis 2001; 38:941. 

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