Wednesday, July 17, 2019

Fever in Adrenal crisis

Q: Low cortisol level? (select one)

A) May mask the fever
B) May exaggerate the fever

Answer: B

Fever secondary to low cortisol can be very deceiving. As sepsis itself can cause low cortisol, it sometimes becomes impossible to determine the actual cause of fever. On the flip side, treating adrenal insufficiency may make the fever go down, and help in the treatment.



1. Bleicken B, Hahner S, Ventz M, Quinkler M. Delayed diagnosis of adrenal insufficiency is common: a cross-sectional study in 216 patients. Am J Med Sci. 2010; 339: 525-531

  2. Dorin R. Qualls C. Crapo L. Diagnosis of adrenal insufficiency. Ann Intern Med. 2003; 139: 194-204

3. Husebye ES Allolio B Arlt W et al. Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency. J Intern Med. 2014; 275: 104-115

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