Q: Which one advantage Fenoldopam has over other parenteral anti-hypertensives?
Answer: Although Fenoldopam is not much-used in ICUs, it is the only parenteral antihypertensive infusion agent, which maintains or increases renal perfusion while it lowers the blood pressure. Fenoldopam is a peripheral dopamine-1 receptor agonist.
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Reference:
Murphy MB, Murray C, Shorten GD. Fenoldopam: a selective peripheral dopamine-receptor agonist for the treatment of severe hypertension. N Engl J Med 2001; 345:1548.
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