Wednesday, December 18, 2019

postprandial syndrome

Q: Postprandial hypoglycemia syndrome requires the nadir of blood glucose to at least which concentration? 

 Answer: None 

 Postprandial hypoglycemia syndrome is not diagnosed by low glucose blood level as studies have shown that there is no correlation between blood glucose concentrations and the occurrence of symptoms during a four-to-six-hour after an oral glucose tolerance test (OGTT). Postprandial hypoglycemia syndrome is a misnomer as this is not a true hypoglycemic disorder. Experts have settled this issue decades ago. This should be referred to as an only postprandial syndrome. It is defined by a time period: symptoms like hypoglycemia i.e. anxiety, weakness, tremor, perspiration, or palpitations occurring within four hours after meals. 


It is a more complex phenomenon, not a diagnosis itself rather symptomatic presentation of an underlying disorder. This syndrome is mostly associated with Post Roux-en-Y gastric bypass, Factitious hypoglycemia from insulin or sulfonylurea, Gin and tonic hypoglycemia, Hereditary fructose intolerance, Insulin autoimmune hypoglycemia, Insulinoma, Noninsulinoma pancreatogenous hypoglycemia syndrome, and Pancreatic transplantation.


#endocrinology

 
References:


1. Johnson DD, Dorr KE, Swenson WM, Service FJ. Reactive hypoglycemia. JAMA 1980; 243:1151. 


2. MCDONALD GW, FISHER GF, BURNHAM C. REPRODUCIBILITY OF THE ORAL GLUCOSE TOLERANCE TEST. Diabetes 1965; 14:473. 


3. Charles MA, Hofeldt F, Shackelford A, et al. Comparison of oral glucose tolerance tests and mixed meals in patients with apparent idiopathic postabsorptive hypoglycemia: absence of hypoglycemia after meals. Diabetes 1981; 30:465.

No comments:

Post a Comment