Q: What is the utility of Plasmodium lactate dehydrogenase (pLDH) in the treatment of Malaria?
pLDH is different in structure from human LDH and is produced by asexual and sexual forms of all Plasmodium species.
pLDH-based assays can be used to predict success or failure of malaria treatment as serum pLDH levels correlate with parasite density and usually become undetectable from blood following antimalarial therapy. It may also identify asymptomatic patients with relatively low parasite densities.
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